IL-6 and IL-11 as markers for tumor aggressiveness and prognosis in gastric adenocarcinoma patients without mutations in Gp130 subunits.

Laura Necula, Mihaela Chivu‐Economescu, Elena L Stanciulescu, Coralia Bleoţu, Simona Dima, Irina Alexiu, Adriana Dumitru, Gabriel Constantinescu, Irinel Popescu, Carmen C. Diaconu

PubMed · 2012 · 53 citations · 18 references

Abstract

According to our results, no mutations were detected in gp130 key positions in human gastric adenocarcinoma samples. However, gp130 activation may occur due to the increased level of IL-6 and IL-11 cytokines detected that can become valuable biomarkers.

References

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