Involvement of Phenolic Metabolites in the Irreversible Protein-Binding of 14C-Bromobenzene Catalysed by Rat Liver Microsomes

Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite

David J. Jollow, John R. Mitchell, Nicola Zampaglione et al. · Pharmacology · 2008 · 3.3K citations

Pharmacy, Pharmacology, Toxicology +17

Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase

Franz Oesch, Donald M. Jerina, John W. Daly et al. · Chemico-Biological Interactions · 1973 · 115 citations

Veterinary Medicine, Pharmacology, Toxicology +16

Microsomal Metabolism of Benzene to Species Irreversibly Binding to Microsomal Protein and Effects of Modifications of This Metabolism

Anders Tunek, Karl L. Platt, P. Bentley et al. · Molecular Pharmacology · 1978 · 109 citations

Pharmacy, Biochemistry, Cellular Metabolism +16

Metabolism of naphthalene to naphthalene dihydrodiol glucuronide in isolated hepatocytes and in liver microsomes

Karl Walter Bock, Gerhard Van Ackeren, Friedrich Lorch et al. · Biochemical Pharmacology · 1976 · 77 citations

Life Sciences, Biochemistry, Toxicology +12

Activation of [14C]chlorobiphenyls to protein-binding metabolites by rat liver microsomes

Sigrun Hesse, Margot Mezger, Thomas Wolff · Chemico-Biological Interactions · 1978 · 48 citations

Medicine, Biochemistry, Pharmacology +11