Contribution of Serine Residues to Constitutive and Agonist-Induced Signaling via the D2SDopamine Receptor: Evidence for Multiple, Agonist-Specific Active Conformations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

O. ARUNLAKSHANA, H. O. Schild · British Journal of Pharmacology and Chemotherapy · 1959 · 4K citations · Full text

Medicine, Pharmacology, General Pharmacology +16

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Identification of Two Serine Residues Involved in Agonist Activation of the β-Adrenergic Receptor

Catherine D. Strader, Mari R. Candelore, W S Hill et al. · Journal of Biological Chemistry · 1989 · 530 citations · Full text

Medicine, Molecular Biology, Pharmacology +13

A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN

Hirotoshi Shimizu, John W. Daly, Cyrus R. Creveling · Journal of Neurochemistry · 1969 · 468 citations

Life Sciences, Biochemistry, Pharmacology +10

Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel

Kevin Wickman, Jorge A. Iñiguez-Lluhı́, P.A. Davenport et al. · Nature · 1994 · 453 citations

Medicine, Cardiology, Physiology +14