Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer

The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

Karl Reinhard Aigner, Brigitta Dampier, Luise Descovich et al. · Oncogene · 2007 · 609 citations · Full text

Transcriptional Regulation, Signal Transduction, Developmental Biology +14

A Transient, EMT-Linked Loss of Basement Membranes Indicates Metastasis and Poor Survival in Colorectal Cancer

Simone Spaderna, Otto Schmalhofer, Falk Hlubek et al. · Gastroenterology · 2006 · 469 citations · Full text

Tumor Biology, Oncology, Medicine +8

Insulin-like Growth Factor-I–Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

Tisheeka Graham, Haiyen E. Zhau, Valerie Odero-Marah et al. · Cancer Research · 2008 · 383 citations

Evidence for a function of CtBP in epithelial gene regulation and anoikis

Madeleine Grooteclaes, Steven M. Frisch · Oncogene · 2000 · 377 citations

Transcriptional Regulation, Systems Biology, Signal Transduction +10

Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition

Natàlia Dave, Sandra Guaita‐Esteruelas, Susana Gutarra et al. · Journal of Biological Chemistry · 2011 · 344 citations · Full text

Molecular Regulation, Cellular Physiology, Transcriptional Regulation +17