Polymer Chemistry · 2016 · 16 citations · 9 references
PharmacyMolecular PharmaceuticsOncologyDrug DeliveryPolymer ChemistryTargeted Drug DeliveryCancer Drug DeliveryCancer NanomedicineNanomaterials For Drug DeliveryNanomedicinePolymeric Drug Delivery SystemsPolymeric NanomaterialsAnticancer Drug LoadingDrug Delivery NanocarriersFluorescent DyesFluorescent PolymersPolymer-mediated Cellular UptakePolymeric NanocarriersTargeted Polymeric CarriersTumor-targeted Drug Delivery
Mitochondria is an attractive target to deliver anticancer drugs. We have synthesized a cationic triphenylphosphonium ion conjugated fluorescent polymer which self-assembles into nanosized polymersomes and targets the encapsulated anticancer drug doxorubicin to cancer cell mitochondria.
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Mitochondrial Dysfunction and Type 2 Diabetes
Bradford B. Lowell, Gerald I. Shulman · Science · 2005 · 2.1K citations
E O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology · 2004 · 1.7K citations · Full text
Medicine, Oncology, Pharmacology +17
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
Nicholas Joza, Santos A. Susín, Éric Daugas et al. · Nature · 2001 · 1.4K citations