Concepedia

Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway

Jiaqi Liu, Jichao Wu, Aili Sun, Yu Sun, Xiangjing Yu, Ning Liu, Shiyun Dong, Fan Yang, Linxue Zhang, Xin Zhong,

Cell & Bioscience · 2016 · 83 citations · 39 references

DOIFull text

Open access

Abstract

Exogenous H2S might protect arterial endothelial cells by suppressing excessive autophagy induced by oxidative stress through the Nrf2-ROS-AMPK signaling pathway.

References

39

Autophagy in the Pathogenesis of Disease

Beth Levine, Guido Kroemer · Cell · 2008 · 6.9K citations · Full text

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.5K citations · Full text

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova, Reuben J. Shaw · Nature Cell Biology · 2011 · 2.9K citations · Full text

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A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

Luca Scorrano, Mona Ashiya, Karolyn Buttle et al. · Developmental Cell · 2002 · 1.1K citations · Full text

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Obesity, Insulin Resistance, Diabetes, and Cardiovascular Risk in Children

Julia Steinberger, Stephen R. Daniels · Circulation · 2003 · 815 citations · Full text