Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Life Sciences, Endocrinology, Immunology +14

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Alexander Wree, Akiko Eguchi, Matthew D. McGeough et al. · Hepatology · 2013 · 934 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hyemi Lee, Jwa-Jin Kim, Hyun Jin Kim et al. · Diabetes · 2012 · 738 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats

Leopoldo Raij, Silvia Azar, William F. Keane · Kidney International · 1984 · 682 citations

Medicine, Nephrology, Pathology +16

Homocysteine as a Predictive Factor for Hip Fracture in Older Persons

Robert R. McLean, Paul F. Jacques, Jacob Selhub et al. · New England Journal of Medicine · 2004 · 594 citations · Full text

Medicine, Geriatric Medicine, Aging +15