Concepedia
The EMBO Journal · 1996 · 55 citations · 29 references
Open access
Life SciencesHematologyMolecular BiologyGene ExpressionMolecular OncologyMolecular VirologyHematopoietic DevelopmentLymphocyte DevelopmentOncogenic Fusion GenesOncogenic VirusesRetinoic Acid SignalingViral OncogenesisPml-rara Fusion Gene
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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
Akira Kakizuka, Wilson H. Miller, Kazuhiko Umesono et al. · Cell · 1991 · 1.5K citations · Full text
Life Sciences, Genetics, Molecular Biology +11
The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
Hugues de Thé, Catherine Lavau, Agnès Marchio et al. · Cell · 1991 · 1.4K citations
Life Sciences, Molecular Biology, Molecular Genetics +10
The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus
Hugues de Thé, Christine Chomienne, Michel Lanotte et al. · Nature · 1990 · 1.4K citations
Life Sciences, Genetics, Molecular Genetics +13
Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)
Raymond P. Warrell, Stanley R. Frankel, Wilson H. Miller et al. · New England Journal of Medicine · 1991 · 1.3K citations · Full text
Medicine, Hematology, Oncology +14
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein
Jacqueline A. Dyck, Gerd G. Maul, Wilson H. Miller et al. · Cell · 1994 · 793 citations
Life Sciences, Biochemistry, Molecular Biology +12