Journal of Huntington s Disease · 2016 · 32 citations · 28 references
These results imply that AUTEN-67 impedes the progression of neurodegenerative symptoms characterizing HD, and that autophagy is a promising therapeutic target for treating this pathology. In humans, AUTEN-67 may have the potential to delay the onset and decrease the severity of HD.
28
Autophagy in the Pathogenesis of Disease
Beth Levine, Guido Kroemer · Cell · 2008 · 6.9K citations · Full text
Autophagy fights disease through cellular self-digestion
Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text