Concepedia

Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation

Xiuting Liu, Wei Zhou, Xin Zhang, Ping Lü, Qianming Du, Lei Tao, Yang Ding, Yajing Wang, Rong Hu

Biochemical Pharmacology · 2016 · 144 citations · 23 references

DOI

Concepts

References

23

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

Rajesh K. Thimmulappa · Journal of Clinical Investigation · 2006 · 1K citations · Full text

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Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

Christian Bauer, Peter Duewell, Christine Mayer et al. · Gut · 2010 · 908 citations · Full text

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Nrf2-Deficient Mice Have an Increased Susceptibility to Dextran Sulfate Sodium–Induced Colitis

Tin Oo Khor, Mou‐Tuan Huang, Ki Han Kwon et al. · Cancer Research · 2006 · 526 citations

, , +16

East–West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

Johan Burisch, N Pedersen, S. Čuković-Čavka et al. · Gut · 2013 · 430 citations · Full text

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