Design, synthesis, and biological evaluation of anti-EV71 agents

An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China

Yan Zhang, Zhen Zhu, Weizhong Yang et al. · Virology Journal · 2010 · 470 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +13

Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers

Frederick G. Hayden, Ronald B. Turner, Jack M. Gwaltney et al. · Antimicrobial Agents and Chemotherapy · 2003 · 235 citations · Full text

Pharmacy, Infectious Diseases, Pharmacology +16

In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Amy K. Patick, Susan L. Binford, M. A. Brothers et al. · Antimicrobial Agents and Chemotherapy · 1999 · 224 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P₁ Lactam Moieties as <scp>l</scp>-Glutamine Replacements

Peter S. Dragovich, Thomas J. Prins, Ru Zhou et al. · Journal of Medicinal Chemistry · 1999 · 189 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

Peter S. Dragovich, Thomas J. Prins, Ru Zhou et al. · Journal of Medicinal Chemistry · 2002 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17