Thomas J. Prins

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

David A. Matthews, Peter S. Dragovich, S. E. Webber et al. · Proceedings of the National Academy of Sciences · 1999 · 316 citations

In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Amy K. Patick, Susan L. Binford, M. A. Brothers et al. · Antimicrobial Agents and Chemotherapy · 1999 · 223 citations · Full text

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P₁ Lactam Moieties as <scp>l</scp>-Glutamine Replacements

Peter S. Dragovich, Thomas J. Prins, Ru Zhou et al. · Journal of Medicinal Chemistry · 1999 · 189 citations · Full text

Bioorganic Chemistry, Antiviral Drug, Viral Structural Protein +18

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

Peter S. Dragovich, Thomas J. Prins, Ru Zhou et al. · Journal of Medicinal Chemistry · 2002 · 140 citations · Full text

A conformational study of peptides with the general structure Ac-L-Xaa-Pro-D-Xaa-L-Xaa-NH2: spectroscopic evidence for a peptide with significant .beta.-turn character in water and in dimethyl sulfoxide

Barbara Imperiali, Rex Moats, Stewart L. Fisher et al. · Journal of the American Chemical Society · 1992 · 114 citations