Tolerance to multiple metal stressors in emerging non-typhoidal MDR<i>Salmonella</i>serotypes: a relevant role for copper in anaerobic conditions

Abstract

This study demonstrates that acquisition of Cu/Ag tolerance genes (sil/pco genes) might contribute to the emergence of particular clinically relevant MDR Salmonella serotypes/clones by facilitating their survival in diverse metal-contaminated settings, particularly in pig production. Assessment of control measures for the use and/or accumulation of metals in diverse environments are needed to prevent a wider expansion of such strains or the emergence of new ones.