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Publication | Open Access

Expression of pro-inflammatory genes in human endothelial cells: Comparison of rivaroxaban and dabigatran

DOIFull Paper Access

71

Citations

22

References

2016

Year

Peter Ellinghaus, Elisabeth Perzborn, Peter Hauenschild, Christoph Gerdes, Stefan Heitmeier, Mayken Visser, Holger Summer, Volker Laux
Thrombosis Research

Abstract

In HUVECs, plasma-induced transcriptional changes are mediated by thrombin-induced PAR-1 activation. Rivaroxaban downregulated the expression of pro-inflammatory markers and tissue factor to a similar extent to dabigatran.

References

YearCitations

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