Disposition of Azole Antifungal Agents. I. Nonlinearities in Ketoconazole Clearance and Binding in Rat Liver

A rapid and simple procedure for chronic cannulation of the rat jugular vein.

P.G. Harms, Sergio R. Ojeda · Journal of Applied Physiology · 1974 · 638 citations

Medicine, Surgery, Vascular Surgery +4

Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes

Yuzo Yoshida, Yuri Aoyama · Biochemical Pharmacology · 1987 · 245 citations

Medicine, Biochemistry, Microbiology +14

KETOCONAZOLE THERAPY FOR ADVANCED PROSTATE CANCER

John Trachtenberg, Allan Pont · The Lancet · 1984 · 164 citations

Medicine, Oncology, Pharmacology +6

Ketoconazole: a potent inhibitor of cytochrome P-450-dependent drug metabolism in rat liver.

Joel J. Sheets, J.Ian Mason · Drug Metabolism and Disposition · 1984 · 124 citations

Medicine, Biochemistry, Pharmacology +17

Pharmacokinetics and dose proportionality of ketoconazole in normal volunteers

Y C Huang, John L. Colaizzi, Robert Bierman et al. · Antimicrobial Agents and Chemotherapy · 1986 · 122 citations

Pharmacy, Pharmacokinetics, Pharmacology +16