Concepedia

Molecular Determinants of Mexiletine Structure for Potent and Use-Dependent Block of Skeletal Muscle Sodium Channels

Annamaria De Luca, F. Natuzzi, Jean‐François Desaphy, Gabriella Loni, Giovanni Lentini, Carlo Franchini, Vincenzo Tortorella, Diana Conte Camerino

Molecular Pharmacology · 2000 · 50 citations · 33 references

DOI

Concepts

References

33

Molecular Determinants of State-Dependent Block of Na <sup>+</sup> Channels by Local Anesthetics

David S. Ragsdale, Jancy C. McPhee, Todd Scheuer et al. · Science · 1994 · 861 citations

, , +17

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.

David S. Ragsdale, Jancy C. McPhee, Todd Scheuer et al. · Proceedings of the National Academy of Sciences · 1996 · 504 citations

, , +16

An improved vaseline gap voltage clamp for skeletal muscle fibers.

Bertil Hille, D. T. Campbell · The Journal of General Physiology · 1976 · 312 citations · Full text

, , +15

Common modes of drug action on Na+ channels: local anesthetics, antiarrhythmics and anticonvulsants

William A. Catterall · Trends in Pharmacological Sciences · 1987 · 290 citations

, , +17

A Common Anticonvulsant Binding Site for Phenytoin, Carbamazepine, and Lamotrigine in Neuronal Na+ Channels

Chung‐Chin Kuo · Molecular Pharmacology · 1998 · 211 citations

, , +17