Glucostatic Mechanism of Regulation of Food Intake

TLDR

Abstract

THE regulation of energy intake is fundamental to all homeostatic mechanisms. Yet this basic process has received less attention than many of the physiologic regulations that it makes possible.Before this century, three theories were advanced to account for the phenomenon of hunger. The theories of peripheral origin (Haller, Erasmus Darwin, Johannes Müller and Weber) held that the taking of food resulted from the stimulation either of all afferent nerves by some change in the tissues or of a strictly local group of sensory nerves, mainly in the stomach. The theory of central origin (Magendie, Tidewald and Milne-Edwards) postulated that . . .