Preparation of fluorinated antibiotics followed by 19F NMR spectroscopy. III Accumulation of 3a-hydroxy-6-fluoroindoline upon addition of 6-fluorotryptophan to the cultured broth of Streptomyces sp. H-63.

Akira Kawashima, Haruo Seto, Masao Katô, Arata Yasuda, Keiichi Uchida, NOBORU TAKE

The Journal of Antibiotics · 1986 · 10 citations · 14 references

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Abstract

Attempts to prepare fluorinated vulgamycins have been followed by 19 NMR spectroscopy. Isolation, structural elucidation and biological activities of fluorovulgamycins are reported.

References

14