Human periodontal ligament stem cells suppress T‐cell proliferation via down‐regulation of non‐classical major histocompatibility complex‐like glycoprotein <scp>CD</scp>1b on dendritic cells

Changsik Shin, Myong Hwan Kim, J.‐A. Han, Bongseo Choi, Daehee Hwang, Jeong‐Ho Yun

Journal of Periodontal Research · 2016 · 45 citations · 38 references

Abstract

This study unveiled an immunomodulatory role of STRO-1<sup>+</sup> CD146<sup>+</sup> PDLSCs in negatively regulating DC-mediated T-cell immune responses, demonstrating their potential to be utilized in promising new stem cell therapies.

References

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