Prevention of Exudative Diathesis in Chicks by Factor 3 and Selenium

Abstract

It is shown that exudative diathesis in the chick, produced by vit. E-free Torula yeast diets, is prevented by crude sources and purified fractions of Factor 3. Selenium, recently identified as the integral part of Factor 3, was highly active. Protection was obtained with 10 μg of selenium per 100 g of diet in form of seleno-cystathionine or sodium selenite; 200 μg of elemental selenium also were effective. All 3 forms of the element stimulated growth.