New England Journal of Medicine · 1955 · 364 citations · 15 references
MedicinePathologySurgeryHistologyHistopathologyWound HealingCollagen DepositionConnective TissueConnective Tissue BreakdownSurgical Wound HealingWound Healing PhysiologyCollagen Matrix ReorganizationConnective Tissue MatrixHealing Tissue FormationHistochemical MarkersTensile StrengthWound Healing PhasesWound Healing Progression
The healing wound remains a perennial focus for surgeons, yet current knowledge mainly addresses factors influencing histological healing sequences and tensile strength gains, and recent studies have introduced diverse.
THE healing wound is of perennial interest and fundamental importance to the surgeon. Despite continued study, however, knowledge to date consists largely of the factors that affect the well known histological sequences of healing and the rate of gain in tensile strength. The intensive inquiries1 , 2 that many investigators have conducted into the nature of connective tissue in the last decade have provided a variety of technics, some old and some new, that require application to the healing wound. This report reappraises the sequences of wound healing on the basis of data obtained from chemical and histochemical studies.Formation of Collagen . . .
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THE DETERMINATION OF COLLAGEN AND ELASTIN IN TISSUES
R. E. Neuman, Milan A. Logan · Journal of Biological Chemistry · 1950 · 819 citations · Full text
Medicine, Anatomy, Biochemistry +7
THE BIOLOGICAL SIGNIFICANCE OF HYALURONIC ACID AND HYALURONIDASE
Karl Meyer · Physiological Reviews · 1947 · 534 citations
Histochemical Demonstration of Acid Polysaccharides in Animal Tissues
Clarence Hale · Nature · 1946 · 381 citations · Full text