Hyaluronic Acid in Pleura Fluid Associated with Malignant Tumor Involving Pleura and Peritoneum

Abstract

Hyaluronic acid in high concentration has been isolated from the chest fluid of a patient with a malignant tumor, probably an endothelioma. The polysaccharide acid in the original fluid migrates in an electric field at pH 7.8 at essentially the same speed as the isolated pure polysaccharide acid, indicating the existence in the fluid of the free acid and not of a protein complex.