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Development and Characteristics of the Rabbit Kidney Cell Strain, LLC-RK1
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1965
Year
Renal PathologyViral PathogenesisPathologyHerpes GroupCellular PhysiologyRenal FunctionKidney Tubule RemodelingRabbit Kidney CellsXenotransplantationVirologyCell BiologyDevelopmental BiologyMolecular VirologyPathogenesisSummarya StrainMedicineAnimal VirusNephrologyKidney Research
SummaryA strain of rabbit kidney cells, LLC-RK1, was developed and carried in serial passage for 5 years. It maintained a near-normal chromosome number and was found not to be transplantable to either young rabbits or suckling hamsters. It was highly susceptible to the herpes group of viruses and also supported the growth of vaccinia, SA-1, rubella, A-1 hepatitis, and RKV. It was insusceptible to the human enteroviruses, influenza and parainfluenza, measles, mumps, adenovirus, varicella, and vesicular stomatitis.