Effects of Insulin and Glucose on Utilization of Fructose by Isolated Rat Diaphragm.

Abstract

In isolated rat diaphragm, insulin increased the metabolism of fructose and glucose via the hexokinase system but did not affect the utilization of fructose via the fructo-kinase pathway. The results suggest that insulin affects the metabolism of glucose and fructose by accelerating their initial phosphorylation by hexokinase.