Concepedia

Hexokinase Regulation

Hexokinase Regulation is a biochemical mechanism that controls the activity of hexokinase, the enzyme catalyzing the initial step of glycolysis, through feedback inhibition, allosteric modulation, and gene expression regulation to maintain cellular glucose homeostasis.

1.5K

Publications

89.2K

Citations

6K

Authors

1.5K

Institutions

Publications per year

2017–2026

299

Parents

Publications

1.5K

Role of the <i>Arabidopsis</i> Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling

Brandon d. Moore, Li Zhou, Filip Rolland et al. · Science · 2003 · 1.2K citations

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Hexokinase as a sugar sensor in higher plants.

Jyan-Chyun Jang, Patricia León, Li Zhou et al. · The Plant Cell · 1997 · 873 citations · Full text

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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Krushna C. Patra, Qi Wang, Prashanth T. Bhaskar et al. · Cancer Cell · 2013 · 859 citations · Full text

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Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

Amparo Wolf, Sameer Agnihotri, Johann Micallef et al. · The Journal of Experimental Medicine · 2011 · 798 citations · Full text

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

Jeffrey C. Rathmell, Casey Fox, David R. Plas et al. · Molecular and Cellular Biology · 2003 · 569 citations · Full text

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1–5 of 1.5K

Authors

6K

  1. JE
    John E. Wilson

    Michigan State University, United States

    33 publications · 1.2K citations

    21

    h-index

  2. HJ
    Herbert J. Fromm

    Iowa State University, United States

    20 publications · 1.1K citations

    18

    h-index

  3. MM
    Mauro Magnani

    University of Urbino, Italy

    20 publications · 564 citations

    15

    h-index

  4. VS
    Vilberto Stocchi

    University of Urbino, Italy

    18 publications · 471 citations

    14

    h-index

  5. FM
    Fernando Moreno

    Universidade de São Paulo, Brazil

    14 publications · 886 citations

    14

    h-index

1–5 of 6K

Institutions

1.5K

  1. Michigan State University

    East Lansing, United States

    26 h-index

    90 publications

    3.5K citations

  2. Harvard University

    Cambridge, United States

    23 h-index

    58 publications

    18K citations

  3. Johns Hopkins University

    Baltimore, United States

    20 h-index

    53 publications

    8.2K citations

  4. Vanderbilt University

    Nashville, United States

    19 h-index

    102 publications

    6.9K citations

  5. University of Urbino

    Urbino, Italy

    18 h-index

    113 publications

    3.3K citations

  6. University of Illinois Chicago

    Chicago, United States

    18 h-index

    93 publications

    15K citations

  7. Iowa State University

    Ames, United States

    17 h-index

    61 publications

    3.5K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    93 publications

    6.8K citations

1–8 of 1.5K

Venues

  1. Journal of Biological Chemistry

    JBC · 96 publications · 8.4K citations

    54

    h-index

  2. Archives of Biochemistry and Biophysics

    ABB · 72 publications · 2.5K citations

    29

    h-index

  3. PubMed

    Repository · 50 publications · 3K citations

    26

    h-index

  4. European Journal of Biochemistry

    EJB · 33 publications · 1.9K citations

    24

    h-index

  5. Biochemical Journal

    BJ · 30 publications · 1.6K citations

    21

    h-index

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