Concepedia

Necrotic, rather than apoptotic, cell death caused by cytochrome P450–activated ifosfamide

Peter Karle, Matthias Renner, Brian Salmons, Walter H. Günzburg

Cancer Gene Therapy · 2001 · 36 citations · 0 references

Concepts

Veterinary MedicineCell BiologyPharmacologyApoptosisDrug MetabolismMechanisms Of ToxicityApoptotic SignalingCell DeathCytochrome P450 InteractionsCytochrome P450-mediated MetabolismNecrosisApoptotic ResponseCytochrome P450 BioactivationCytochrome P450 OxidationCytotoxic NecrosisDrug-induced Apoptosis