Peter Karle

Development of Cellulose Sulfate‐based Polyelectrolyte Complex Microcapsules for Medical Applications

Horst Dautzenberg, Ute Schuldt, G. Grasnick et al. · Annals of the New York Academy of Sciences · 1999 · 106 citations

Pharmacy, Bioengineering, Biotechnology +17

Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450

Matthias Löhr, Petra Müller, Peter Karle et al. · Gene Therapy · 1998 · 97 citations

Medicine, Oncology, Pharmacology +15

Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma: a phase I/II study

Matthias Löhr, Zoltán Bagó, Helga Bergmeister et al. · Journal of Molecular Medicine · 1999 · 58 citations

Medicine, Oncology, Pharmacology +8

Necrotic, rather than apoptotic, cell death caused by cytochrome P450–activated ifosfamide

Peter Karle, Matthias Renner, Brian Salmons et al. · Cancer Gene Therapy · 2001 · 36 citations

Veterinary Medicine, Cell Biology, Pharmacology +13

Injection of Encapsulated Cells Producing an Ifosfamide‐Activating Cytochrome P450 for Targeted Chemotherapy to Pancreatic Tumors

Petra Müller, Ralf Jesnowski, Peter Karle et al. · Annals of the New York Academy of Sciences · 1999 · 33 citations

Medicine, Oncology, Pharmacology +12