The Effects of a 5-Lipoxygenase Inhibitor on Asthma Induced by Cold, Dry Air

Abstract

Selective inhibition of 5-lipoxygenase by A-64077 is associated with a significant amelioration of the asthmatic response to cold, dry air, suggesting that 5-lipoxygenase products are involved in this response. This approach may be useful in the treatment of asthma.