Cyclothialidine, a novel DNA gyrase inhibitor. I. Screening, taxonomy, fermentation and biological activity.

Junko Watanabe, Naoki Nakada, SAYOKO SAWAIRI, H Shimada, SHOICHI OHOICHI, Tsutomu Kamiyama, Mikio Arisawa

The Journal of Antibiotics · 1994 · 31 citations · 6 references

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Abstract

Streptomyces filipinensis NR 0484 produced a new DNA gyrase inhibitor, cyclothialidine. It showed potent activity against DNA gyrases from Escherichia coli and Micrococcus luteus.

References

6