A novel strategy for the generation of angiostatic kringle regions from a precursor derived from plasminogen

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

Noel Weidner, Joseph P. Semple, William R. Welch et al. · New England Journal of Medicine · 1991 · 5.7K citations

Medicine, Cancer Biology, Oncology +15

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

M. OʼReilly · Cell · 1994 · 3.4K citations

Medicine, Oncology, Pharmacology +14

Angiostatin induces and sustains dormancy of human primary tumors in mice

Michael S. O’Reilly, Lars Holmgren, Catherine Chen et al. · Nature Medicine · 1996 · 1.2K citations

Medicine, Oncology, Pharmacology +16

Macrophage-Derived Metalloelastase Is Responsible for the Generation of Angiostatin in Lewis Lung Carcinoma

Zhongyun Dong, Rakesh Kumar, Xiulan Yang et al. · Cell · 1997 · 531 citations · Full text

Medicine, Cancer Biology, Cell Biology +14

Kringle Domains of Human Angiostatin

Yihai Cao, Richard W. Ji, Donald J. Davidson et al. · Journal of Biological Chemistry · 1996 · 365 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +9