IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes

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Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

Life Sciences, Genetics, Molecular Biology +14

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

Life Sciences, Immunology, Molecular Biology +14

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

Joël Raingeaud, Shashi Kumar Gupta, Jeffrey S. Rogers et al. · Journal of Biological Chemistry · 1995 · 2.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

Toshio Hirano, Kiyoshi Yasukawa, Hisashi Harada et al. · Nature · 1986 · 2.2K citations

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