Cell-free expression of the APP transmembrane fragments with Alzheimer's disease mutations using algal amino acid mixture for structural NMR studies

A Continuous Cell-Free Translation System Capable of Producing Polypeptides in High Yield

Alexander S. Spirin, Vladimir Baranov, Lyubov A. Ryabova et al. · Science · 1988 · 602 citations

Life Sciences, Biotechnology, Molecular Biology +11

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

Franz Hagn, Manuel Etzkorn, Thomas Raschle et al. · Journal of the American Chemical Society · 2013 · 513 citations · Full text

Natural Sciences, Biochemistry, Biophysics +17

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

Lisa Marie Munter, Philipp Voigt, Anja Harmeier et al. · The EMBO Journal · 2007 · 283 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Structural Studies of the Transmembrane C-Terminal Domain of the Amyloid Precursor Protein (APP): Does APP Function as a Cholesterol Sensor?

Andrew J. Beel, Charles K. Mobley, Hak Jun Kim et al. · Biochemistry · 2008 · 176 citations

Life Sciences, Molecular Biology, Neuroscience +17

Amyloidogenic Processing but Not Amyloid Precursor Protein (APP) Intracellular C-terminal Domain Production Requires a Precisely Oriented APP Dimer Assembled by Transmembrane GXXXG Motifs

Pascal Kienlen‐Campard, Bernadette Tasiaux, Joanne Van Hees et al. · Journal of Biological Chemistry · 2008 · 140 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17