Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

Franz Hagn, Manuel Etzkorn, Thomas Raschle, +1

Journal of the American Chemical Society

Membrane StructureProteinlipid InteractionEngineeringBiomolecular Structure PredictionMembrane Proteins +14

A conserved spider silk domain acts as a molecular switch that controls fibre assembly

Franz Hagn, Lukas Eisoldt, John G. Hardy, +4

Nature

Pattern FormationMolecular BiologyMolecular SwitchFibre AssemblyMedicine +1

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Mahmoud L. Nasr, Diego Baptista, Mike Strauss, +8

Nature Methods

NanoparticlesEngineeringProtein NanoparticlesNanomaterialsNanotechnology +5

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

Marco Retzlaff, Franz Hagn, Lars Mitschke, +4

Molecular Cell

Protein FunctionBiochemistryProtein AssemblyProtein FoldingNatural Sciences +5

The architecture of functional modules in the Hsp90 co‐chaperone Sti1/Hop

Andreas Schmid, Stephan Lagleder, Melissa Ann Gräwert, +9

The EMBO Journal

Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR

Franz Hagn, Mahmoud L. Nasr, Gerhard Wagner

Nature Protocols

Membrane StructureProteinlipid InteractionBiochemistryStructural BiologyProtein Nmr +6

Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function

Sylvia Welker, Birgit Rudolph, Elke Frenzel, +10

Molecular Cell

Proteinlipid InteractionProtein FunctionUnstructured Stress ProteinProtein FoldingNatural Sciences +8

pH‐Dependent Dimerization and Salt‐Dependent Stabilization of the N‐terminal Domain of Spider Dragline Silk—Implications for Fiber Formation

Franz Hagn, Christopher Thamm, Thomas Scheibel, +1

Angewandte Chemie International Edition

Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53

Franz Hagn, Stephan Lagleder, Marco Retzlaff, +5

Nature Structural & Molecular Biology

Protein FunctionMedicineNatural SciencesMolecular BiologyStructural Analysis +5

Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs

Meng Zhang, Miao Gui, Zifu Wang, +12

Nature Structural & Molecular Biology

Proteinlipid InteractionLipid NanodiscsBiochemistryMedicineMembrane Biology +4