Die Naturwissenschaften · 1979 · 16 citations · 10 references
MedicineMedicinal ChemistryPharmacologyMolecular PharmacologyPharmacodynamicsSynthetic Medicinal ChemistryEnzyme InhibitionLigand BindingNeuropeptide PharmacologyPeptide Drug DiscoveryPeptide Medicinal Chemistry
10
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations
Analgesia induced in vivo by central administration of enkephalin in rat
James D. Belluzzi, Norman H. Grant, Victor M. Garsky et al. · Nature · 1976 · 528 citations
A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity
D. Roemer, Heinz Buescher, Ronald C. Hill et al. · Nature · 1977 · 395 citations