Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

Apoptotic Program, Biochemistry, Medicine +11

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations

Caspase-activated Dnase, Natural Sciences, Apoptosis +8

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell · 1997 · 3.1K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +12

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Protein Chemistry, Biochemistry, Viral Polymerase Structure +6

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Cell · 1993 · 2.5K citations · Full text

Cytokine, Signaling Pathway, Cell Regulation +11