Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato, +15

Nature

Rig-i HelicasesVirus StructureViral ReplicationProtein FoldingRna Structure Prediction +9

A diverse range of gene products are effectors of the type I interferon antiviral response

John W. Schoggins, Sam J. Wilson, Maryline Panis, +4

Nature

PathogenesisImmunologyAntiviral ResponseAntiviral Drug DevelopmentVirology +6

<i>mda-5</i>: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

Dong-chul Kang, Rahul V. Gopalkrishnan, Qingping Wu, +3

Proceedings of the National Academy of Sciences

Characterization of a novel ranavirus isolated from grouper Epinephelus tauvina

SF Chang, G. H. Ngoh‐Lim, Susan Gibson‐Kueh, +2

Diseases of Aquatic Organisms

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

Mingxian Chang, Bertrand Collet, Pin Nie, +4

Journal of Virology

Rainbow TroutGeneticsImmunologyRetinoic Acid-inducible GeneIfn Production +23

Characterization of two grouper Epinephelus akaara cell lines: Application to studies of Singapore grouper iridovirus (SGIV) propagation and virus–host interaction

Xiaohong Huang, Youhua Huang, Jingjing Sun, +2

Aquaculture

Virus–host InteractionPathogenesisVirologyVirus ClassificationSingapore Grouper Iridovirus +5

Functional Genomics Analysis of Singapore Grouper Iridovirus: Complete Sequence Determination and Proteomic Analysis

Wen Song, Qi Qin, Jin Qiu, +3

Journal of Virology

GeneticsGenomicsFunctional Genomics AnalysisViral EvolutionEntire Sgiv Genome +15

Transcriptome analysis of orange-spotted grouper (Epinephelus coioides) spleen in response to Singapore grouper iridovirus

Youhua Huang, Xiaohong Huang, Yan Yang, +5

BMC Genomics

Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo

Leonid Gitlin, Loralyn A. Benoît, Christina Song, +4

PLoS Pathogens

Molecular cloning, expression and functional analysis of ISG15 in orange-spotted grouper, Epinephelus coioides

Xiaohong Huang, Youhua Huang, Jia Cai, +3

Fish & Shellfish Immunology

BiosynthesisBioorganic ChemistryEngineeringBiochemistryOrange-spotted Grouper +5