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Electron Microscopic Analysis of Chromosome Metabolism in the Drosophila melanogaster Embryo
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1978
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CytogeneticsGeneticsMolecular GeneticsReproductive BiologyEpigeneticsEmbryologyDrosophila MelanogasterChromatin TranscriptionElectron Microscopic ProceduresDrosophila Melanogaster EmbryoGameteDna ReplicationChromatin BiologyNuclear OrganizationChromosomal RearrangementChromatin FunctionBiologyChromatinChromosome MetabolismElectron Microscopic AnalysisDevelopmental BiologyChromatin StructureChromatin RemodelingNatural SciencesChromosome BiologyMedicine
Information regarding the patterns of chromatin transcription and replication is important in understanding the mechanisms regulating genome metabolism. Electron microscopic procedures provide a useful tool for the study of chromosome function. We have chosen to apply the technique of chromatin spreading to Drosophila melanogaster as it is a well-studied biological system that is amenable to cytogenetic manipulation.