Sesquiterpenes and a monoterpenoid with acetylcholinesterase (AchE) inhibitory activity from Valeriana officinalis var. latiofolia in vitro and in vivo

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

Life Sciences, Biochemistry, Pharmacology +14

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: Relationships to β-amyloid deposition and neurotransmitter abnormalities

Alena Savonenko, Guilian Xu, Tatiana Melnikova et al. · Neurobiology of Disease · 2005 · 394 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man

Peter Leathwood, F. Chauffard, Eva Heck et al. · Pharmacology Biochemistry and Behavior · 1982 · 229 citations

Life Sciences, Botany, Pharmacology +12

Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties

Miguel Hattesohl, Björn Feistel, Hartwig Sievers et al. · Phytomedicine · 2007 · 156 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Neurobehavioral abnormalities in the dysbindin‐1 mutant, sandy, on a C57BL/6J genetic background

Michael M. Cox, Aimee M. Tucker, Jianmin Tang et al. · Genes Brain & Behavior · 2009 · 109 citations · Full text

Life Sciences, Genetics, Neuroscience +16