Concepedia

Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways

Xuqiang Nie, Huaihong Chen, Jianyong Zhang, Yujing Zhang, Jianwen Yang, Huijun Pan, Wenxia Song, Ferid Murad, Yuqi He, Ka Bian

Acta Pharmacologica Sinica · 2016 · 90 citations · 47 references

DOI

Concepts

References

47

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

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Protection from obesity-induced insulin resistance in mice lacking TNF-α function

K. Teoman Uysal, Sarah M. Wiesbrock, Michael W. Marino et al. · Nature · 1997 · 2.2K citations

, , +14

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

Philip A. Kern, Subramanian Ranganathan, Chunling Li et al. · American Journal of Physiology-Endocrinology and Metabolism · 2001 · 1.9K citations

, , +17

IKK-β links inflammation to obesity-induced insulin resistance

Melek C. Arkan, Andrea L. Hevener, Florian R. Greten et al. · Nature Medicine · 2005 · 1.8K citations

, , +14

The High-Fat Diet–Fed Mouse

Maria Sörhede Winzell, Bo Åhrén · Diabetes · 2004 · 1K citations · Full text

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