Nature Biotechnology · 2016 · 382 citations · 23 references
Life SciencesBioinformaticsOncologyCancer GeneticsGenomicsMolecular OncologyCancer GenomicsComputational OncologyGenetic Risk AssessmentGermline Cancer PredispositionGermline Cancer SusceptibilityMolecular Tumor ProfilingCancer Vulnerability MappingCancer Vulnerability ProfilingCell Line Sensitivity ProfilingCellular Genotype InferenceComputational Cancer GenomicsPrecision Oncology GenomicsTumor Mutation Analysis
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.5K citations
Medicine, Oncology, Pharmacology +15
Systematic identification of genomic markers of drug sensitivity in cancer cells
Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.6K citations · Full text
Medicine, Cancer Biology, Oncology +16
A quantitative analysis of kinase inhibitor selectivity
Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations
Comprehensive analysis of kinase inhibitor selectivity
Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology · 2011 · 2.4K citations · Full text
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Keith T. Flaherty, Caroline Robert, Peter Hersey et al. · New England Journal of Medicine · 2012 · 2.1K citations · Full text
Medicine, Oncology, Pharmacology +17