Concepedia

Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model

Manal Amoury, Katharina Kolberg, Anh‐Tuan Pham, Dmitrij Hristodorov, Radoslav Mladenov, Stefano Fiore, Wijnand Helfrich, Rainer Fischer, Alessa Pardo, Theophilus Thepen,

Cancer Letters · 2016 · 43 citations · 43 references

DOI

Concepts

References

43

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Brian D. Lehmann, Joshua A. Bauer, Xi Chen et al. · Journal of Clinical Investigation · 2011 · 5.5K citations · Full text

, , +17

An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9

Hua Zou, Yuchen Li, Xuesong Liu et al. · Journal of Biological Chemistry · 1999 · 2.1K citations · Full text

, , +17

2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial

Ian Smith, Marion Procter, Richard D. Gelber et al. · The Lancet · 2007 · 1.5K citations

, , +15

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

Irène Baccelli, Andreas Schneeweiß, Sabine Riethdorf et al. · Nature Biotechnology · 2013 · 1K citations

, , +16

Frequent EpCam protein expression in human carcinomas

Philip Went, Alessandro Lugli, Sandra Meier et al. · Human Pathology · 2004 · 826 citations

, , +13