Concepedia

The Role of the Immune Response in the Pathogenesis of Thyroid Eye Disease: A Reassessment

James T. Rosenbaum, Dongseok Choi, Amanda Wong, David J. Wilson, Hans E. Grossniklaus, Christina A. Harrington, Roger A. Dailey, John D. Ng, Eric A. Steele, Craig N. Czyz,

PLoS ONE · 2015 · 22 citations · 23 references

DOIFull text

Open access

Abstract

This is the first study to compare gene expression in TED to gene expression associated with other causes of exophthalmos. The juxtaposition shows that inflammatory markers are far less characteristic of TED relative to other orbital inflammatory diseases.

References

23

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 54.5K citations · Full text

, , +23

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.4K citations

, , +10

Summaries of Affymetrix GeneChip probe level data

Rafael A. Irizarry · Nucleic Acids Research · 2003 · 4.9K citations · Full text

Randomized Controlled Trial of Rituximab in Patients With Graves' Orbitopathy

Marius N. Stan, James A. Garrity, Barbara Gisella Carranza Leon et al. · The Journal of Clinical Endocrinology & Metabolism · 2014 · 349 citations · Full text

Cytokine Profiles in Eye Muscle Tissue and Orbital Fat Tissue from Patients with Thyroid-Associated Ophthalmopathy*

Yuji Hiromatsu, Dame Yang, Tomasz Bednarczuk et al. · The Journal of Clinical Endocrinology & Metabolism · 2000 · 183 citations · Full text