LASER THERAPY · 2015 · 43 citations · 20 references
EngineeringDermatologySurgeryBiomedical OpticsBiophotonicsTissue EngineeringAbsorption In TissueLaser SurgeryLight-emitting DiodesLight-tissue InteractionTissue OpticsTissue Responses To RadiationAction Potential GenerationBruisingBruising PreventionBruising ReductionDermal RegenerationLight-based TherapyOptical Characterization Of Biological TissuePhototherapy Devices
BACKGROUND: Aggressive, or even minimally aggressive, aesthetic interventions are almost inevitably followed by such events as discomfort, erythema, edema and hematoma formation which could lengthen patient downtime and represent a major problem to the surgeon. Recently, low level light therapy with light-emitting diodes (LED-LLLT) at 830 nm has attracted attention in wound healing indications for its anti-inflammatory effects and control of erythema, edema and bruising. RATIONALE: The wavelength of 830 nm offers deep penetration into living biological tissue, including bone. A new-generation of 830 nm LEDs, based on those developed in the NASA Space Medicine Laboratory, has enabled the construction of planar array-based LED-LLLT systems with clinically useful irradiances. Irradiation with 830 nm energy has been shown in vitro and in vivo to increase the action potential of epidermal and dermal cells significantly. The response of the inflammatory stage cells is enhanced both in terms of function and trophic factor release, and fibroblasts demonstrate superior collagenesis and elastinogenesis. CONCLUSIONS: A growing body of clinical evidence is showing that applying 830 nm LED-LLLT as soon as possible post-procedure, both invasive and noninvasive, successfully hastens the resolution of sequelae associated with patient downtime in addition to significantly speeding up frank wound healing. This article reviews that evidence, and attempts to show that 830 nm LED-LLLT delivers swift resolution of postoperative sequelae, minimizes downtime and enhances patient satisfaction.
20
Macrophage responsiveness to light therapy
Steve Young, Peter Bolton, Mary Dyson et al. · Lasers in Surgery and Medicine · 1989 · 329 citations
C. Baxter, George W. Waylonis · American Journal of Physical Medicine & Rehabilitation · 1995 · 182 citations
Seung Yoon Lee, Jung-Woo Choi, Jung-Kyun Kwon et al. · Journal of Photochemistry and Photobiology B Biology · 2007 · 182 citations