Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

Life Sciences, Genetics, Molecular Genetics +17

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

Maria Mańczak, Thimmappa S. Anekonda, Edward Henson et al. · Human Molecular Genetics · 2006 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

P. Hemachandra Reddy, M. Flint Beal · Trends in Molecular Medicine · 2008 · 970 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17