Concepedia

Macrophage Recruitment and Polarization During Collateral Vessel Remodeling in Murine Adipose Tissue

Scott A. Seaman, Yiqi Cao, Chris A. Campbell, Shayn M. Peirce

Microcirculation · 2015 · 24 citations · 35 references

DOI

Abstract

Our study describes microvascular adaptations in adipose in response to altered blood flow and underscores the importance of macrophages. Our data supports the development of therapies that target macrophages in order to enhance vascular remodeling in flaps.

References

35

Genomic responses in mouse models poorly mimic human inflammatory diseases

Junhee Seok, H. Shaw Warren, Alex G. Cuenca et al. · Proceedings of the National Academy of Sciences · 2013 · 2.9K citations · Full text

Analysis of Fractalkine Receptor CX<sub>3</sub>CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Steffen Jung, Júlio Aliberti, Petra Graemmel et al. · Molecular and Cellular Biology · 2000 · 2.6K citations · Full text

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Daniel J. Ceradini, Anita R. Kulkarni, Matthew J. Callaghan et al. · Nature Medicine · 2004 · 2.6K citations

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Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.

Michael Stein, Satish Keshav, Nicholas Harris et al. · The Journal of Experimental Medicine · 1992 · 1.9K citations · Full text

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Macrophage activation switching: an asset for the resolution of inflammation

Fabrice Porcheray, Sophie Viaud, A.C. Rimaniol et al. · Clinical & Experimental Immunology · 2005 · 826 citations · Full text