Concepedia

Publication | Open Access

Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a–JNK Signaling

DOIFull Paper Access

115

Citations

35

References

2016

Year

Rosa Bretón‐Romero, Bihua Feng, Monika Holbrook, Melissa G. Farb, Jessica L. Fetterman, Erika A Linder, Brittany Berk, Nobuyuki Masaki, Robert M. Weisbrod, Elica Inagaki,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our findings demonstrate that noncanonical Wnt5a signaling and JNK activity contribute to vascular insulin resistance and endothelial dysfunction and may represent a novel therapeutic opportunity to protect the vasculature in patients with diabetes mellitus.

References

YearCitations

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