The Effect of Genetic Polymorphism on the Inhibition of Azole Antifungal Agents Against CYP2C9-Mediated Metabolism

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes

Toshiro Niwa, Toshifumi Shiraga, Akira Takagi · Biological and Pharmaceutical Bulletin · 2005 · 271 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase

Charles L. Crespi, Vaughn P. Miller · Pharmacogenetics · 1997 · 267 citations

Medicine, Biochemistry, Pharmacology +16

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population

Maria Gabriella Scordo, Eleni Aklillu, Ümit Yaşar et al. · British Journal of Clinical Pharmacology · 2001 · 223 citations · Full text

Medicine, Genetics, Pharmacology +15