Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

Gregg L. Semenza, G.L. Wang · Molecular and Cellular Biology · 1992 · 2.4K citations · Full text

Protein Synthesis Binds, Genetics, Redox Biology +16

T-cell apoptosis detected in situ during positive and negative selection in the thymus

Charles D. Surh, Jonathan Sprent · Nature · 1994 · 1.1K citations

T-cell Apoptosis, T-regulatory Cell, Apoptosis +10

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

Noelia A-González, Steven J. Bensinger, Cynthia Hong et al. · Immunity · 2009 · 657 citations · Full text

Nuclear Receptor Lxr, Immune Tolerance, Autoimmune Disease +10

Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms.

Yi Zhu, Chao Qi, Julie R. Korenberg et al. · Proceedings of the National Academy of Sciences · 1995 · 645 citations · Full text

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

Kodi S. Ravichandran · The Journal of Experimental Medicine · 2010 · 532 citations · Full text