Age and Ageing · 1984 · 94 citations · 0 references
Public HealthGeriatric MedicineNutritional SciencesDementiaGeriatricsMicronutrient DeficiencyAlzheimer DiseaseFolate DeficiencyMicronutrient Needs In Older AdultsVitamin B12 DeficiencyVitamin B12 PhysiologyVitamin PhysiologyAlzheimer Disease DementiaB VitaminsMicronutrient Deficiencies In AgingSerum Folate StatusVitamin B12 (Cobalamin)Vitamin B12 Deficiency PhysiologyVitamin B12 MetabolismVitamin B12 Status Biomarkers
Serum vitamin B12 levels (as determined by radio-immunoassay) were measured in 20 subjects aged 65 years and over with Alzheimer-type dementia, 20 age-matched subjects with non-Alzheimer type dementia and 20 age-matched subjects with no dementia. Serum vitamin B12 levels were significantly lower and serum vitamin B12 deficiency was significantly more frequent in subjects with Alzheimer-type dementia and were independent of age, sex, haematological abnormality or serum folate.