Concepedia

Clinical Trial to Assess the Safety, Feasibility, and Efficacy of Transferring a Potentially Anti-Arthritic Cytokine Gene to Human Joints with Rheumatoid Arthritis. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Christopher H. Evans, Henry J. Mankin, Paul D. Robbins, Steve Ghivizzani, James H. Herndon, Richard W. Kang, Alfred B. Bahnson, John A. Barranger, Elaine M. Elders, Steffen Gay,

Human Gene Therapy · 1996 · 248 citations · 14 references

DOI

Concepts

References

14

Transplantation Proceedings

Surgery · 2006 · 1.7K citations

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

Jeremy Saklatvala · Nature · 1986 · 744 citations · Full text

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Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

Robert E. Donahue, Steven Kessler, David M. Bodine et al. · The Journal of Experimental Medicine · 1992 · 537 citations · Full text

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Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

E. R. Pettipher, G.A. Higgs, Brian E. Henderson · Proceedings of the National Academy of Sciences · 1986 · 494 citations · Full text

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Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction

David J. Dripps, Barbara J. Brandhuber, Richard Thompson et al. · Journal of Biological Chemistry · 1991 · 454 citations · Full text